Safe steps in food handling, cooking, and storage can prevent foodborne illness. There are four basic steps to food safety at home:

• Clean - always wash your fruits and vegetables, hands, counters, and cooking utensils.
• Separate - keep raw foods to themselves. Germs can spread from one food to another.
• Cook - foods need to get hot and stay hot. Heat kills germs.
• Chill - put fresh food in the refrigerator right away.

In the grocery store, avoid cans that are bulging or jars that have cracks or loose lids. Check packages to be sure food hasn't reached its expiration date.

United States Department of Agriculture

Your gallbladder is a pear-shaped organ under your liver. It stores bile, a fluid made by your liver to digest fat. As your stomach and intestines digest food, your gallbladder releases bile through a tube called the common bile duct. The duct connects your gallbladder and liver to your small intestine.

Your gallbladder is most likely to give you trouble if something blocks the flow of bile through the bile ducts. That is usually a gallstone. Gallstones form when substances in bile harden. Rarely, you can also get cancer in your gallbladder.

Many gallbladder problems get better with removal of the gallbladder. Fortunately, you can live without a gallbladder. Bile has other ways of reaching your small intestine.

Your digestive or gastrointestinal (GI) tract includes the esophagus, stomach, small intestine, large intestine or colon, rectum, and anus. Bleeding can come from any of these areas. The amount of bleeding can be so small that only a lab test can find it.

Signs of bleeding in the digestive tract depend on where it is and how much bleeding there is.

Signs of bleeding in the upper digestive tract include:

• Bright red blood in vomit
• Vomit that looks like coffee grounds
• Black or tarry stool
• Dark blood mixed with stool

Signs of bleeding in the lower digestive tract include:

• Black or tarry stool
• Dark blood mixed with stool
• Stool mixed or coated with bright red blood

GI bleeding is not a disease, but a symptom of a disease. There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus.

The test used most often to look for the cause of GI bleeding is called endoscopy. It uses a flexible instrument inserted through the mouth or rectum to view the inside of the GI tract. A type of endoscopy called colonoscopy looks at the large intestine.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Genetic disorders are health conditions caused by changes (also called mutations or variants) in your genes. Genes are parts of DNA found in your cells that carry instructions for how your body grows, develops, and functions. Many genes tell your body how to make proteins, which are needed for your body to work properly.

A genetic disorder happens when a gene variant changes how a protein is made. The variant may cause the protein to work poorly or not be made at all. If genes don't make the right proteins, or don't make them correctly, it can lead to a genetic disorder.

Not all gene changes cause disease. Often, these changes have no effect. But sometimes, even a small change in DNA can affect how proteins are made.

Gene variants can be grouped into two main types:

• Inherited variants (also called germline variants) are passed down from your parents. They come from egg or sperm cells.
• Non-inherited (also called somatic variants) are not passed down from your parents. They happen during your lifetime. They may be caused by things like harmful chemicals or ultraviolet (UV) rays from the sun.

Genetic disorders may be caused by:

• Single gene disorders are caused by changes in one gene. Examples can include sickle cell anemia, where a change in a single gene can cause the condition, and Charcot-Marie-Tooth disease, where a variant in one of many different genes can cause the condition.
• Chromosomal disorders are caused by missing, extra, or altered chromosomes. Chromosomes are structures that carry genes. These disorders involve changes in the number of chromosomes people have or changes in the structure of one or more chromosomes. An example is Down syndrome, which is caused by an extra copy of chromosome 21.
• Complex (multifactorial) disorders are caused by changes in many genes. Each change alone may not cause the disease, but together they increase the risk. Lifestyle and environmental factors, such as exercise, diet, or exposure to pollutants, also play a role. Colon cancer is an example.

Some genetic conditions are passed down through families (inherited) in one of several patterns, depending on the specific gene involved.

Patterns of inheritance can include:

• Dominant means you only need one changed gene to cause the condition.
• Recessive means you need two changed copies of the gene (one from each parent) for the condition to occur.
• X-linked conditions involve genes located on the X chromosome. These conditions often affect males more frequently.
• Mitochondrial conditions are passed down by the mother.

Your health care provider may check for a genetic condition based on:

• A physical examination.
• Your personal medical history.
• Your family health history.
• Laboratory tests, including genetic testing.

NIH: National Library of Medicine

Genital warts are a sexually transmitted infection (STI) caused by the human papillomavirus (HPV). There are many types of HPV. Some types of HPV can cause genital warts. Other types of HPV can cause cancer.

There is no treatment for HPV, but your health care provider can treat genital warts. HPV vaccines may help prevent some of the HPV infections that cause genital warts.

If you are sexually active, you can get genital warts during oral, vaginal, or anal sex with an infected partner. You can still get genital warts even if they are so small that you can't see them.

It doesn't happen often, but genital warts can also be spread from a woman to her baby during childbirth.

Genital warts are often painless and may not cause any symptoms. You might not even know that you have them. Sometimes, they can also cause itching, burning, bleeding, or discomfort.

The warts usually appear as a small bump or group of bumps in the genital area. They are flesh-colored and can be flat or look bumpy like cauliflower.

Your provider can usually find out if you have genital warts by seeing them during a physical exam or pelvic exam. In women, the warts usually occur in or around the vagina, on the cervix, or around the anus. Men may have warts on the tip of the penis, around the anus, or on the scrotum, thigh, or groin.

The warts might disappear on their own, stay the same, or grow bigger or increase in number. A few ways that your provider can treat them include:

• Use medicines, cream, or ointment
• Remove them by burning, freezing, or cutting out the warts

HPV stays in your body even after treatment. This means that warts can come back, and you can still spread HPV to others after genital warts are removed.

Getting an HPV vaccine may help prevent genital warts. HPV vaccines provide the most protection if you get them before exposure to the virus. This means that it's best to get vaccinated before becoming sexually active. If you're over age 26 and haven't been vaccinated, talk with your provider about the possible benefits of vaccination.

Correct usage of latex condoms greatly reduces, but does not eliminate, the risk of catching or spreading HPV. If you or your partner is allergic to latex, you can use polyurethane condoms. The best way to avoid infection is not to have anal, vaginal, or oral sex.

Dept. of Health and Human Services Office on Women's Health